
Dr. Fry
Dr Frye is a Harvard trained Child Neurologist with expertise in neurodevelopmental and
neurometabolic disorders. He received an MD and PhD in Physiology and Biophysics from
Georgetown University. He completed a residency in Pediatrics at the University of Miami,
Residency in Child Neurology and Fellowship in Behavioral Neurology and Learning Disabilities
at Harvard University/Children’s Hospital Boston and Fellowship in Psychology at Boston
University. He also received a Masters in Biomedical Science and Biostatistics from Drexel
University. He holds board certifications in Pediatrics, and in Neurology with Special
Competence in Child Neurology. He has authored over 300 publications and book chapters and
serves on several editorial boards.
Dr. Frye is a national leader in autism spectrum disorder (ASD) research, particularly metabolic
disorders, and has authored over 300 publications. He has developed the Metabolic Learning
Resource which has recently released The Folate Fix. He is President and Chief Scientific
Officer of the Autism Discovery and Treatment Foundation, Chief Medical Officer of the
Neurological Health Foundation, Director of Research and Neurologist at the Rossignol Medical
Center.
He has lead several clinical studies on children with ASD, including studies focusing on defining
the clinical, behavioral, cognitive, genetic and metabolic characteristics of children with ASD and
mitochondrial disease and several clinical trials demonstrating the efficacy of safe and novel
treatments that target underlying physiological abnormalities in children with ASD, including
studies on leucovorin, cobalamin and tetrahydrobiopterin and has an ongoing multicenter
controlled clinical trial on leucovorin, neuroimmune modulators and photobiomodulation.
